Self-Assembled Polymeric Micellar Nanoparticles as Nanocarriers for Poorly Soluble Anticancer Drug Ethaselen

Self-Assembled Polymeric Micellar Nanoparticles as Nanocarriers for Poorly Soluble Anticancer Drug Ethaselen

<p>Abstract</p> <p>A series of monomethoxy poly(ethylene glycol)-poly(lactide) (mPEG-PLA) diblock copolymers were synthesized, and mPEG-PLA micelle was fabricated and used as a nanocarrier for solubilization and delivery of a promising anticancer drug ethaselen. Ethaselen was effic...

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Bibliographic Details
Main Authors: Yang Zhuoli, Ren Lijun, Yang Kewei, Li Xinru, Zhou Yanxia, Chen Xingwei, Zhang Yanhui, Wang Fei, Liu Yan
Format: Article
Language:English
Published: SpringerOpen 2009-01-01
Series:Nanoscale Research Letters
Subjects:
Monomethoxy poly(ethylene glycol)-poly(lactide)
Polymeric micelles
Hemolysis
Ethaselen
Antitumor efficacy
Online Access:http://dx.doi.org/10.1007/s11671-009-9427-2

Internet

http://dx.doi.org/10.1007/s11671-009-9427-2

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