Ammonia-Induced Brain Edema Requires Macrophage and T Cell Expression of Toll-Like Receptor 9Summary

Background & Aim: Ammonia is central in the pathogenesis of brain edema in acute liver failure (ALF) with infection and systemic inflammation expediting development of intracranial hypertension (ICH). Patients with acetaminophen-induced ALF have increased neutrophil TLR9 expression which can be...

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Bibliographic Details
Main Authors: Godhev Kumar Manakkat Vijay, Changyun Hu, Jian Peng, Irma Garcia-Martinez, Rafaz Hoque, Rejina Mariam Verghis, Yun Ma, Wajahat Zafar Mehal, Debbie Lindsay Shawcross, Li Wen
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300992