Over 40 Years of Fosmidomycin Drug Research: A Comprehensive Review and Future Opportunities

Over 40 Years of Fosmidomycin Drug Research: A Comprehensive Review and Future Opportunities

To address the continued rise of multi-drug-resistant microorganisms, the development of novel drugs with new modes of action is urgently required. While humans biosynthesize the essential isoprenoid precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) via the established m...

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Bibliographic Details
Main Authors: Talea Knak, Mona A. Abdullaziz, Stefan Höfmann, Leandro A. Alves Avelar, Saskia Klein, Matthew Martin, Markus Fischer, Nobutada Tanaka, Thomas Kurz
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
DXR/IspC inhibitor
fosmidomycin
malaria
<i>Plasmodium falciparum</i>
<i>Mycobacterium tuberculosis</i>
PfDXR
Online Access:https://www.mdpi.com/1424-8247/15/12/1553

Internet

https://www.mdpi.com/1424-8247/15/12/1553

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