Effect of calcium ions on the aggregation of highly phosphorylated tau

Tau is typically an axonal protein, but in neurons of brains affected by Alzheimer's disease (AD), aggregation of hyperphosphorylated tau in the somatodendritic compartment causes neuronal death. We have previously demonstrated that tau mRNA is transported within dendrites and undergoes immedia...

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Bibliographic Details
Main Authors: Toru Tanaka, Sachiyo Ohashi, Akihiko Takashima, Shunsuke Kobayashi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824002516