Low‐dose TNF augments fracture healing in normal and osteoporotic bone by up‐regulating the innate immune response

Low‐dose TNF augments fracture healing in normal and osteoporotic bone by up‐regulating the innate immune response

Abstract The mechanism by which trauma initiates healing remains unclear. Precise understanding of these events may define interventions for accelerating healing that could be translated to the clinical arena. We previously reported that addition of low‐dose recombinant human TNF (rhTNF) at the frac...

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Bibliographic Details
Main Authors: James K Chan, Graeme E Glass, Adel Ersek, Andrew Freidin, Garry A Williams, Kate Gowers, Ana I Espirito Santo, Rosemary Jeffery, William R Otto, Richard Poulsom, Marc Feldmann, Sara M Rankin, Nicole J Horwood, Jagdeep Nanchahal
Format: Article
Language:English
Published: Springer Nature 2015-05-01
Series:EMBO Molecular Medicine
Subjects:
bone
CCL2
fracture
inflammation
TNF
Online Access:https://doi.org/10.15252/emmm.201404487

Internet

https://doi.org/10.15252/emmm.201404487

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