One gene to rule them all…and in the darkness bind them

Pharmaceutical inhibition of the Human Epidermal growth factor Receptor 2 (HER2) oncogene has dramatically improved outcomes in HER2-amplified breast cancers. However, monotherapy HER2 inhibitors are not effective. We have recently reported that a co-amplified microRNA within the HER2 amplicon, lead...

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Detalhes bibliográficos
Main Authors: Konstantinos V. Floros, Anthony C. Faber
Formato: Artigo
Idioma:English
Publicado em: Taylor & Francis Group 2018-07-01
Colecção:Molecular & Cellular Oncology
Assuntos:
Acesso em linha:http://dx.doi.org/10.1080/23723556.2018.1465881