Atomic resolution protein allostery from the multi-state structure of a PDZ domain

Atomic resolution protein allostery from the multi-state structure of a PDZ domain

In this manuscript the authors report accurate multi-state protein structures of the PDZ domain using biological NMR. By looking into protein structural states, the authors report an allosteric pathway at atomic resolution that validates previously reported low resolution findings and uncovered a st...

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Bibliographic Details
Main Authors: Dzmitry Ashkinadze, Harindranath Kadavath, Aditya Pokharna, Celestine N. Chi, Michael Friedmann, Dean Strotz, Pratibha Kumari, Martina Minges, Riccardo Cadalbert, Stefan Königl, Peter Güntert, Beat Vögeli, Roland Riek
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33687-x

Internet

https://doi.org/10.1038/s41467-022-33687-x

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