VEGFR2 inhibition hampers breast cancer cell proliferation via enhanced mitochondrial biogenesis

VEGFR2 inhibition hampers breast cancer cell proliferation via enhanced mitochondrial biogenesis

Objective: Vascular endothelial growth factor (VEGF), apart from its predominant roles in angiogenesis, can enhance cancer cell proliferation, but its mechanisms remain elusive. The purpose of the present study was therefore to identify how VEGF regulates cancer cell proliferation. Methods: VEGF eff...

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Bibliographic Details
Main Authors: Hao Ni, Min Guo, Xuepei Zhang, Lei Jiang, Shuai Tan, Juan Yuan, HuanhuanL Cui, Yanan Min, Junhao Zhang, Susanne Schlisio, Chunhong Ma, Wangjun Liao, Monica Nister, Chunlin Chen, Shuijie Li, Nailin Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2021-02-01
Series:Cancer Biology & Medicine
Subjects:
breast cancer
vegf
vegfr2
mitochondria
tfam
ros
apoptosis
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1776

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1776

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