A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1

Fatty acid desaturases (FADS) play an important role in the formation of omega-6 and omega-3 highly unsaturated fatty acids (HUFAs). The composition of HUFAs in the human metabolome is important for membrane fluidity and for the modulation of essential physiological functions such as inflammation pr...

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Bibliographic Details
Main Authors: E. Lattka, S. Eggers, G. Moeller, K. Heim, M. Weber, D. Mehta, H. Prokisch, T. Illig, J. Adamski
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313882