Turmeric Bioactive Compounds Alleviate Spinal Nerve Ligation-Induced Neuropathic Pain by Suppressing Glial Activation and Improving Mitochondrial Function in Spinal Cord and Amygdala

Turmeric Bioactive Compounds Alleviate Spinal Nerve Ligation-Induced Neuropathic Pain by Suppressing Glial Activation and Improving Mitochondrial Function in Spinal Cord and Amygdala

This study examined the effects of turmeric bioactive compounds, curcumin C3 complex® (CUR) and bisdemethoxycurcumin (BDMC), on mechanical hypersensitivity and the gene expression of markers for glial activation, mitochondrial function, and oxidative stress in the spinal cord and amygdala of rats wi...

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Bibliographic Details
Main Authors: Julianna M. Santos, Rui Wang, Viren Bhakta, Zarek Driver, Yakhnitsa Vadim, Takaki Kiritoshi, Guangchen Ji, Volker Neugebauer, Chwan-Li Shen
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Nutrients
Subjects:
curcumin
pain
neuroinflammation
brain
animal
Online Access:https://www.mdpi.com/2072-6643/15/20/4403

Internet

https://www.mdpi.com/2072-6643/15/20/4403

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