Vaccine efficacy against malaria by the combination of porcine parvovirus-like particles and vaccinia virus vectors expressing CS of Plasmodium.

With the aim to develop an efficient and cost-effective approach to control malaria, we have generated porcine parvovirus-like particles (PPV-VLPs) carrying the CD8(+) T cell epitope (SYVPSAEQI) of the circumsporozoite (CS) protein from Plasmodium yoelii fused to the PPV VP2 capsid protein (PPV-PYCS...

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Bibliographic Details
Main Authors: Dolores Rodríguez, Gloria González-Aseguinolaza, Juan R Rodríguez, Aneesh Vijayan, Magdalena Gherardi, Paloma Rueda, J Ignacio Casal, Mariano Esteban
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3328484?pdf=render