Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Abstract Background Cachexia‐associated skeletal muscle wasting or ‘sarcopenia’ is highly prevalent in ovarian cancer and contributes to poor outcome. Drivers of cachexia‐associated sarcopenia in ovarian cancer remain elusive, underscoring the need for novel and better models to identify tumour fact...

詳細記述

書誌詳細
主要な著者: Jorne Ubachs, Wouter R.P.H. van deWorp, Rianne D.W. Vaes, Kenneth Pasmans, Ramon C. Langen, Ruth C.R. Meex, Annemarie A.J.H.M. vanBijnen, Sandrina Lambrechts, Toon Van Gorp, Roy F.P.M. Kruitwagen, Steven W.M. Olde Damink, Sander S. Rensen
フォーマット: 論文
言語:English
出版事項: Wiley 2022-02-01
シリーズ:Journal of Cachexia, Sarcopenia and Muscle
主題:
Protein synthesis
Protein breakdown
Atrogenes
NF‐κB
Interleukin‐6
C2C12 cells
オンライン･アクセス:https://doi.org/10.1002/jcsm.12885

インターネット

https://doi.org/10.1002/jcsm.12885

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