Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Abstract Background Cachexia‐associated skeletal muscle wasting or ‘sarcopenia’ is highly prevalent in ovarian cancer and contributes to poor outcome. Drivers of cachexia‐associated sarcopenia in ovarian cancer remain elusive, underscoring the need for novel and better models to identify tumour fact...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Jorne Ubachs, Wouter R.P.H. van deWorp, Rianne D.W. Vaes, Kenneth Pasmans, Ramon C. Langen, Ruth C.R. Meex, Annemarie A.J.H.M. vanBijnen, Sandrina Lambrechts, Toon Van Gorp, Roy F.P.M. Kruitwagen, Steven W.M. Olde Damink, Sander S. Rensen
Format:	Artykuł
Język:	English
Wydane:	Wiley 2022-02-01
Seria:	Journal of Cachexia, Sarcopenia and Muscle
Hasła przedmiotowe:	Protein synthesis Protein breakdown Atrogenes NF‐κB Interleukin‐6 C2C12 cells
Dostęp online:	https://doi.org/10.1002/jcsm.12885

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