Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein

Reactivation of human cytomegalovirus in immunosuppressed transplant patients can cause severe complications. Here, Krishnaet al. show that a fusion toxin protein that specifically binds the viral surface protein US28 can be used to kill latently infected monocytes and their progenitor cells in vitr...

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Xehetasun bibliografikoak
Egile Nagusiak: B. A. Krishna, K. Spiess, E. L. Poole, B. Lau, S. Voigt, T. N. Kledal, M. M. Rosenkilde, J. H. Sinclair
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Nature Portfolio 2017-02-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/ncomms14321