Hippo Signaling Mediates TGFβ-Dependent Transcriptional Inputs in Cardiac Cushion Mesenchymal Cells to Regulate Extracellular Matrix Remodeling

Hippo Signaling Mediates TGFβ-Dependent Transcriptional Inputs in Cardiac Cushion Mesenchymal Cells to Regulate Extracellular Matrix Remodeling

The transforming growth factor beta (TGFβ) and Hippo signaling pathways are evolutionarily conserved pathways that play a critical role in cardiac fibroblasts during embryonic development, tissue repair, and fibrosis. TGFβ signaling and Hippo signaling are also important for cardiac cushion remodeli...

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Bibliographic Details
Main Authors: Mrinmay Chakrabarti, Ahad Chattha, Abhijith Nair, Kai Jiao, Jay D. Potts, Lianming Wang, Scotty Branch, Shea Harrelson, Saeed Khan, Mohamad Azhar
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
transforming growth factor beta
Hippo
cushion mesenchyme
heart valve
extracellular matrix
Online Access:https://www.mdpi.com/2308-3425/10/12/483

Internet

https://www.mdpi.com/2308-3425/10/12/483

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