Fosfomycin Pharmacokinetic Profile in Plasma and Urine and Quantitative Estimation in Prostate and Seminal Vesicles after One and Two Consecutive Doses of Oral Fosfomycin Trometamol in Healthy Male Volunteers

Fosfomycin Pharmacokinetic Profile in Plasma and Urine and Quantitative Estimation in Prostate and Seminal Vesicles after One and Two Consecutive Doses of Oral Fosfomycin Trometamol in Healthy Male Volunteers

The present Phase I study investigated, for the first time, fosfomycin pharmacokinetics in humans after two 3 g doses of fosfomycin trometamol administered 27 h apart, according to the dose regimen recommended for the prophylactic indication for transrectal prostate biopsy in adult men. Plasma, urin...

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Bibliographic Details
Main Authors: Andrea F. D. Di Stefano, Milko M. Radicioni, Francesca Morano, Alessandra Gentili, Elena Mallat, Dario Cuomo, Tonia Mazzarella, Veronica Di Fonzo
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antibiotics
Subjects:
fosfomycin trometamol
pharmacokinetics
male genital tract
prostate
noninvasive
quantitation
Online Access:https://www.mdpi.com/2079-6382/11/11/1458

Internet

https://www.mdpi.com/2079-6382/11/11/1458

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