RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation

RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation

Summary: Although the small GTPase RAB37 acts as an organizer of autophagosome biogenesis, the upstream regulatory mechanism of autophagy via guanosine diphosphate (GDP)-guanosine triphosphate (GTP) exchange in maintaining retinal function has not been determined. We found that retinitis pigmentosa...

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Bibliographic Details
Main Authors: Ruhong Ying, Cong Li, Huirong Li, Juan Zou, Mengxin Hu, Qiang Hong, Yin Shen, Ling Hou, Hanhua Cheng, Rongjia Zhou
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
CP: Molecular biology
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724003383

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http://www.sciencedirect.com/science/article/pii/S2211124724003383

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