Diesterified derivatives of 5-iodo-2'-deoxyuridine as cerebral tumor tracers.

With the aim to develop beneficial tracers for cerebral tumors, we tested two novel 5-iodo-2'-deoxyuridine (IUdR) derivatives, diesterified at the deoxyribose residue. The substances were designed to enhance the uptake into brain tumor tissue and to prolong the availability in the organism. We...

Full description

Bibliographic Details
Main Authors: Thomas W Rösler, Andreas Matusch, Damiano Librizzi, Oscar Arias-Carrión, Nils Freundlieb, Helmut Hoeffken, Wolfgang H Oertel, Candan Depboylu, Günter U Höglinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25028935/?tool=EBI