Extracellular matrix and cyclic stretch alter fetal cardiomyocyte proliferation and maturation in a rodent model of heart hypoplasia

Extracellular matrix and cyclic stretch alter fetal cardiomyocyte proliferation and maturation in a rodent model of heart hypoplasia

IntroductionBirth defects, particularly those that affect development of the heart, are a leading cause of morbidity and mortality in infants and young children. Babies born with heart hypoplasia (heart hypoplasia) disorders often have a poor prognosis. It remains unclear whether cardiomyocytes from...

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Bibliographic Details
Main Authors: Matthew C. Watson, Corin Williams, Raymond M. Wang, Luke R. Perreault, Kelly E. Sullivan, Whitney L. Stoppel, Lauren D. Black
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiomyocytes
proliferation
heart hypoplasia
extracellular matrix (ECM)
mechanical stretch
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.993310/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.993310/full

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