Disruption of Glutamate Release and Uptake-Related Protein Expression After Noise-Induced Synaptopathy in the Cochlea

Disruption of Glutamate Release and Uptake-Related Protein Expression After Noise-Induced Synaptopathy in the Cochlea

High-intensity noise can cause permanent hearing loss; however, short-duration medium-intensity noise only induces a temporary threshold shift (TTS) and damages synapses formed by inner hair cells (IHCs) and spiral ganglion nerves. Synaptopathy is generally thought to be caused by glutamate excitoto...

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Bibliographic Details
Main Authors: Kefeng Ma, Anran Zhang, Xiaojun She, Honglian Yang, Kun Wang, Yingwen Zhu, Xiujie Gao, Bo Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
noise
synaptopathy
Vglut3
GLAST
Na+/K+-ATPase α1
glutamate excitotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.720902/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.720902/full

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