Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial

Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial

Background The cysteine protease legumain is increased in patients with atherosclerosis, but its causal role in atherogenesis and cardiovascular disease is still unclear. The aim of the study was to investigate the association of legumain with clinical outcome in a large cohort of patients with acut...

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Bibliographic Details
Main Authors: Ida Gregersen, Annika E. Michelsen, Ngoc Nguyen Lunde, Axel Åkerblom, Tatevik G. Lakic, Mona Skjelland, Karolina Ryeng Skagen, Richard C. Becker, Johan Lindbäck, Anders Himmelmann, Rigmor Solberg, Harald T. Johansen, Stefan K. James, Agneta Siegbahn, Robert F. Storey, Frederic Kontny, Pål Aukrust, Thor Ueland, Lars Wallentin, Bente Halvorsen
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
acute coronary syndromes
ischemic stroke
legumain
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.016360

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.016360

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