Age-dependent recombination rates in human pedigrees.
In humans, chromosome-number abnormalities have been associated with altered recombination and increased maternal age. Therefore, age-related effects on recombination are of major importance, especially in relation to the mechanisms involved in human trisomies. Here, we examine the relationship betw...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-09-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3164683?pdf=render |