Integrated control of bacterial growth and stress response by (p)ppGpp in Escherichia coli: A seesaw fashion

Summary: To thrive in nature, bacteria have to reproduce efficiently under favorable conditions and persist during stress. The global strategy that integrates the growth control and stress response remains to be explored. Here, we find that a moderate induction of (p)ppGpp reduces growth rate but si...

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Bibliographic Details
Main Authors: Manlu Zhu, Haoyan Mu, Xiongfeng Dai
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000397