Practical basket design for binary outcomes with control of family-wise error rate

Abstract Background A basket trial is a type of clinical trial in which eligibility is based on the presence of specific molecular characteristics across subpopulations with different cancer types. The existing basket designs with Bayesian hierarchical models often improve the efficiency of evaluati...

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Bibliographic Details
Main Authors: Junichi Asano, Hiroyuki Sato, Akihiro Hirakawa
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-023-01872-1