Practical basket design for binary outcomes with control of family-wise error rate
Abstract Background A basket trial is a type of clinical trial in which eligibility is based on the presence of specific molecular characteristics across subpopulations with different cancer types. The existing basket designs with Bayesian hierarchical models often improve the efficiency of evaluati...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
|
Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-023-01872-1 |