Preventive HIPEC in combination with perioperative FLOT versus FLOT alone for resectable diffuse type gastric and gastroesophageal junction type II/III adenocarcinoma – the phase III “PREVENT”- (FLOT9) trial of the AIO /CAOGI /ACO

Preventive HIPEC in combination with perioperative FLOT versus FLOT alone for resectable diffuse type gastric and gastroesophageal junction type II/III adenocarcinoma – the phase III “PREVENT”- (FLOT9) trial of the AIO /CAOGI /ACO

Abstract Background The main reason for treatment failure after curative surgical resection of gastric cancer is intra-abdominal spread, with 40–50% peritoneal seeding as primary localization of recurrence. Peritoneal relapse is seen in 60–70% of tumors of diffuse type, compared to only 20–30% of in...

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Bibliographic Details
Main Authors: Thorsten O. Götze, Pompiliu Piso, Sylvie Lorenzen, Ulli S. Bankstahl, Claudia Pauligk, Moustafa Elshafei, Giuseppe Amato, Daniel Reim, Wolf O. Bechstein, Alfred Königsrainer, Stefan P. Mönig, Beate Rau, Matthias Schwarzbach, Salah-Eddin Al-Batran
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Cancer
Subjects:
Gastric cancer
Gastroesophageal junction cancer
Lauren- classification
Signet ring cells
HIPEC
Hyperthermic intraperitoneal chemotherapy
Online Access:https://doi.org/10.1186/s12885-021-08872-8

Internet

https://doi.org/10.1186/s12885-021-08872-8

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