One-Step Suicide Substrate Inactivation Kinetics of a Ping-Pong Reaction with One Substrate Undergoing Disproportionation: A Theoretical Approach with Approximate Solutions

Understanding the kinetic mechanism of enzyme inactivation by suicide substrate is of relevance for the optimal design of new drugs with pharmacological and therapeutic applications. Suicide substrate inactivation usually occurs via a two-step mechanism, although there are enzymes such as peroxidase...

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Bibliographic Details
Main Authors: Ismael Gutiérrez-Fernández, Ouardia Bendou, Nara Bueno-Ramos, Emilio L. Marcos-Barbero, Rosa Morcuende, Juan B. Arellano
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/10/22/4240