Eutectic Mixture Formation and Relaxation Dynamics of Coamorphous Mixtures of Two Benzodiazepine Drugs

Eutectic Mixture Formation and Relaxation Dynamics of Coamorphous Mixtures of Two Benzodiazepine Drugs

The formation of coamorphous mixtures of pharmaceuticals is an interesting strategy to improve the solubility and bioavailability of drugs, while at the same time enhancing the kinetic stability of the resulting binary glass and allowing the simultaneous administration of two active principles. In t...

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Bibliographic Details
Main Authors: Sofia Valenti, Claudio Cazorla, Michela Romanini, Josep Lluís Tamarit, Roberto Macovez
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
valium
coamorphous formulations
dielectric spectroscopy
glass transition
ring-inversion
physical stability of glasses
Online Access:https://www.mdpi.com/1999-4923/15/1/196

Internet

https://www.mdpi.com/1999-4923/15/1/196

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