G-Quadruplex Matters in Tissue-Specific Tumorigenesis by BRCA1 Deficiency

How and why distinct genetic alterations, such as <i>BRCA1</i> mutation, promote tumorigenesis in certain tissues, but not others, remain an important issue in cancer research. The underlying mechanisms may reveal tissue-specific therapeutic vulnerabilities. Although the roles of BRCA1,...

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Bibliographic Details
Main Authors: Sanghyun Kim, Sohyun Hwang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/3/391