Recombinant Zika virus envelope protein elicited protective immunity against Zika virus in immunocompetent mice.

Zika virus (ZIKV) has caused great public concerns due to its recent large outbreaks and a close association with microcephaly in fetus and Guillain-Barre syndrome in adults. Rapid development of vaccines against ZIKV is a public health priority. To this end, we have constructed and purified recombi...

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Bibliographic Details
Main Authors: Huabin Liang, Ruoheng Yang, Zhihua Liu, Min Li, Haitao Liu, Xia Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5874044?pdf=render