Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma

Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma

Abstract Background Patient derived xenografts (PDX) are generated by transplanting the original patient’s tumor tissue into immune-deficient mice. Unlike xenograft models derived from cell lines, PDX models can better preserve the histopathology from the original patient and molecular pathways. Hig...

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Bibliographic Details
Main Authors: Ruifen Dong, Wenan Qiang, Haiyang Guo, Xiaofei Xu, J. Julie Kim, Andrew Mazar, Beihua Kong, Jian-Jun Wei
Format: Article
Language:English
Published: BMC 2016-09-01
Series:Journal of Hematology & Oncology
Subjects:
High-grade serous carcinoma
Patient-derived xenograft
Intrabursal engraft histology
Immunohistochemistry
Online Access:http://link.springer.com/article/10.1186/s13045-016-0318-6

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http://link.springer.com/article/10.1186/s13045-016-0318-6

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