Real-Life Vancomycin Therapeutic Drug Monitoring in Coagulase-Negative Staphylococcal Bacteremia in Neonatal and Pediatric Intensive Care Unit: Are We Underestimating Augmented Renal Clearance?

Real-Life Vancomycin Therapeutic Drug Monitoring in Coagulase-Negative Staphylococcal Bacteremia in Neonatal and Pediatric Intensive Care Unit: Are We Underestimating Augmented Renal Clearance?

Bloodstream infections (BSI) from coagulase-negative-staphylococci (CoNS) are among the most frequent healthcare-related infections. Their treatment involves the use of vancomycin, a molecule whose optimal pharmacokinetic/pharmacodynamic (PK/PD) target for efficacy and safety is an area-under-curve/...

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Bibliographic Details
Main Authors: Claudia Sette, Marcello Mariani, Luca Grasselli, Alessio Mesini, Carolina Saffioti, Chiara Russo, Roberto Bandettini, Andrea Moscatelli, Luca A. Ramenghi, Elio Castagnola
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Antibiotics
Subjects:
vancomycin
PK/PD
TDM
augmented renal clearance
Online Access:https://www.mdpi.com/2079-6382/12/11/1566

Internet

https://www.mdpi.com/2079-6382/12/11/1566

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