Lipoxygenase-derived oxylipins are enriched in anti-citrullinated protein antibody (ACPA)-positive individuals at risk for developing rheumatoid arthritis

Lipoxygenase-derived oxylipins are enriched in anti-citrullinated protein antibody (ACPA)-positive individuals at risk for developing rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is typically preceded by an extended preclinical period where circulating autoantibodies, particularly anti-citrullinated protein antibodies (ACPA), are detectable in the absence of clinical arthritis. Increased dietary intake of anti-inflammatory omega-...

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Bibliographic Details
Main Authors: Liam J. O’Neil, Vidyanand Anaparti, Tanja Winter, Irene Smolik, Xiaobo Meng, Harold M. Aukema, Hani El-Gabalawy
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
ω-6 fatty acids
ω-3 fatty acids
Oxylipins
Preclinical RA
Polyunsaturated fatty acids
Online Access:https://doi.org/10.1186/s13075-024-03274-0

Internet

https://doi.org/10.1186/s13075-024-03274-0

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