NUCLEAR GENE MUTATIONS AS THE CAUSE OF MITOCHONDRIAL COMPLEX III DEFICIENCY

Complex III (CIII) deficiency is one of the least common oxidative phosphorylation defects associated to mitochondrial disease. CIII constitutes the center of the mitochondrial respiratory chain, as well as a crossroad for several other metabolic pathways. For more than ten years, of all the potenti...

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Bibliographic Details
Main Authors: Erika eFernandez-Vizarra, Massimo eZeviani
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00134/full