Modulation of mitochondrial activity by sugarcane (Saccharum officinarum L.) top extract and its bioactive polyphenols: a comprehensive transcriptomics analysis in C2C12 myotubes and HepG2 hepatocytes

Modulation of mitochondrial activity by sugarcane (Saccharum officinarum L.) top extract and its bioactive polyphenols: a comprehensive transcriptomics analysis in C2C12 myotubes and HepG2 hepatocytes

Abstract Age-related mitochondrial dysfunction leads to defects in cellular energy metabolism and oxidative stress defense systems, which can contribute to tissue damage and disease development. Among the key regulators responsible for mitochondrial quality control, peroxisome proliferator-activated...

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Bibliographic Details
Main Authors: Kengo Iwata, Farhana Ferdousi, Yoshinobu Arai, Hiroko Isoda
Format: Article
Language:English
Published: SpringerOpen 2024-01-01
Series:Natural Products and Bioprospecting
Subjects:
Sugarcane top
Polyphenol
Mitochondria
PGC-1α
Fatty acid metabolism
Inflammatory cytokine
Online Access:https://doi.org/10.1007/s13659-023-00423-x

Internet

https://doi.org/10.1007/s13659-023-00423-x

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