Molecular analysis of 76 Chinese hemophilia B pedigrees and the identification of 10 novel mutations

Molecular analysis of 76 Chinese hemophilia B pedigrees and the identification of 10 novel mutations

Abstract Background Hemophilia B (HB) is an X‐linked recessive inherited bleeding disorder caused by mutations in the F9 gene that lead to plasma factor IX deficiency. To identify the causative mutations in HB, a molecular analysis of HB pedigrees in China was performed. Methods Using next‐generatio...

Full description

Bibliographic Details
Main Authors: Limin Huang, Liyan Li, Sheng Lin, Juanjuan Chen, Kun Li, Dongmei Fan, Wangjie Jin, Yihong Li, Xu Yang, Yufeng Xiong, Fenxia Li, Xuexi Yang, Ming Li, Qiang Li
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
F9
hemophilia B
molecular diagnosis
next‐generation sequencing
Online Access:https://doi.org/10.1002/mgg3.1482

Internet

https://doi.org/10.1002/mgg3.1482

Similar Items