Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol

Introduction There remains an unmet need for safe and cost-effective adjunctive treatment of advanced colorectal cancer (CRC). The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) is safe, well-tolerated and has anti-inflammatory as well as antineoplastic properties. A phase 2 randomis...

Full description

Bibliographic Details
Main Authors: Helen Marshall, Mark A Hull, David A Cairns, Andrew T Chan, Mingyang Song, Robert Jones, Peter S Hall, Catherine Moriarty, David A Drew, Wendy S Garrett, Giles J Toogood, Paul M Loadman, Andrew J Cockbain, Omer Yilmaz, Pei Loo Ow, Sharon Ruddock, Tim Brend, Alexandra F Smith, Fiona Collinson
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/11/e077427.full