Deep transfer learning for inter-chain contact predictions of transmembrane protein complexes

Abstract Membrane proteins are encoded by approximately a quarter of human genes. Inter-chain residue-residue contact information is important for structure prediction of membrane protein complexes and valuable for understanding their molecular mechanism. Although many deep learning methods have bee...

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Bibliographic Details
Main Authors: Peicong Lin, Yumeng Yan, Huanyu Tao, Sheng-You Huang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40426-3