Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells

<p>Abstract</p> <p>Background</p> <p>In estrogen responsive MCF-7 cells, estradiol (E<sub>2</sub>) binding to ERα leads to transcriptional regulation of genes involved in the control of cell proliferation and survival. MicroRNAs (miRNAs) have emerged as key...

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Bibliographic Details
Main Authors: Yu Xinfeng, Zhang Xuemei, Dhakal Ishwori B, Beggs Marjorie, Kadlubar Susan, Luo Dali
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/29