Discovery of a small molecule that inhibits Bcl-3-mediated cyclin D1 expression in melanoma cells

Abstract Molecular targeted therapy using a drug that suppresses the growth and spread of cancer cells via inhibition of a specific protein is a foundation of precision medicine and treatment. High expression of the proto-oncogene Bcl-3 promotes the proliferation and metastasis of cancer cells origi...

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Váldodahkkit: Karunakar Saamarthy, Kristofer Ahlqvist, Renée Daams, Navisraj Balagunaseelan, Agnes Rinaldo-Matthis, Julhash U. Kazi, Wondossen Sime, Ramin Massoumi
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: BMC 2024-01-01
Ráidu:BMC Cancer
Fáttát:
Liŋkkat:https://doi.org/10.1186/s12885-023-11663-y