Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 Signaling

Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 Signaling

Cardiac hypertrophy can lead to congestive heart failure and is a leading cause of morbidity and mortality worldwide. In recent years, it has been essential to find the treatment and prevention of cardiac hypertrophy. Betulinic acid (BA), the main active ingredient in many natural products, is known...

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Bibliographic Details
Main Authors: Mi-Hyeon Hong, Se-Won Na, Youn-Jae Jang, Jung-Joo Yoon, Yun-Jung Lee, Ho-Sub Lee, Hye-Yoom Kim, Dae-Gill Kang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Nutrients
Subjects:
betulinic acid
cardiac hypertrophy
isoprenaline
calcineurin-NFATc3 signaling
Online Access:https://www.mdpi.com/2072-6643/13/10/3484

Internet

https://www.mdpi.com/2072-6643/13/10/3484

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