Simultaneous Expression of Different Therapeutic Genes by Infection with Multiple Oncolytic HSV-1 Vectors

Simultaneous Expression of Different Therapeutic Genes by Infection with Multiple Oncolytic HSV-1 Vectors

Oncolytic viruses (OVs) are anti-cancer therapeutics combining the selective killing of cancer cells with the triggering of an anti-tumoral immune response. The latter effect can be improved by arming OVs with immunomodulatory factors. Due to the heterogeneity of cancer and the tumor microenvironmen...

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Bibliographic Details
Main Authors: Adriana Vitiello, Alberto Reale, Valeria Conciatori, Anna Vicco, Alfredo Garzino-Demo, Giorgio Palù, Cristina Parolin, Jens von Einem, Arianna Calistri
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Biomedicines
Subjects:
virotherapy
immunotherapy
HSV-1
combinatorial approach
Online Access:https://www.mdpi.com/2227-9059/12/7/1577

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https://www.mdpi.com/2227-9059/12/7/1577

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