Feedback loop between hypoxia and energy metabolic reprogramming aggravates the radioresistance of cancer cells

Abstract Radiotherapy is one of the mainstream approaches for cancer treatment, although the clinical outcomes are limited due to the radioresistance of tumor cells. Hypoxia and metabolic reprogramming are the hallmarks of tumor initiation and progression and are closely linked to radioresistance. I...

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Bibliographic Details
Main Authors: Zheng Shi, Cuilan Hu, Xiaogang Zheng, Chao Sun, Qiang Li
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40164-024-00519-1