The role of voltage-gated chloride channels in the epileptogenesis of temporal lobe epilepsy

The role of voltage-gated chloride channels in the epileptogenesis of temporal lobe epilepsy

Background: Temporal lobe epilepsy (TLE) is the most common intractable epilepsy in adults, and elucidation of the underlying pathological mechanisms is needed. Voltage-gated chloride channels (ClC) play diverse physiological roles in neurons. However, less is known regarding their functions in the...

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Bibliographic Details
Main Authors: Kai-Feng Shen, Xiao-Lin Yang, Guo-Long Liu, Gang Zhu, Zhong-Ke Wang, Xian-Jun Shi, Ting-Ting Wang, Zhi-Feng Wu, Sheng-Qing Lv, Shi-Yong Liu, Hui Yang, Chun-Qing Zhang
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EBioMedicine
Subjects:
Temporal lobe epilepsy
Voltage-gated chloride channels
Chloride channel blockers
High-frequency oscillations
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003303

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http://www.sciencedirect.com/science/article/pii/S2352396421003303

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