96 shRNAs designed for maximal coverage of HIV-1 variants

<p>Abstract</p> <p>Background</p> <p>The RNA interference (RNAi) pathway is a mechanism of gene-suppression with potential gene therapy applications for treating viral disease such as HIV-1. The most suitable inducer of RNAi for this application is short hairpin RNA (sh...

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Bibliographic Details
Main Authors: Shen Sylvie, Jaramillo Angel, Yu Yi-Hsin, Groneman Jennifer, Mcintyre Glen, Applegate Tanya
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/55