Preparation of Memantine-Loaded Chitosan Nanocrystals: In Vitro and Ex Vivo Toxicity Analysis

Preparation of Memantine-Loaded Chitosan Nanocrystals: In Vitro and Ex Vivo Toxicity Analysis

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with unmet medical need, and is the leading cause of age-related dementia affecting millions of people worldwide. This work aims at developing small, high-drug loading capacity (DL) and -entrapment efficiency (EE) memantine hydroch...

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Bibliographic Details
Main Authors: Mohamed A. Saleh, Jamal M. M. Mohamed, J. Joysa Ruby, Selvakumar Kanthiah, Yasmene F. Alanazi, Kamlah A. Majrashi, Sultan M. Alshahrani, Mohamed Ahmed Eladl, Fatima S. Alaryani, Mohamed El-Sherbiny, Farid Menaa
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Crystals
Subjects:
memantine HCl/chitosan nanocrystals
ionic gelation method
Alzheimer’s disease
neurodegenerative disorder
nanomedicine
innovation
Online Access:https://www.mdpi.com/2073-4352/13/1/21

Internet

https://www.mdpi.com/2073-4352/13/1/21

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