Integration of virtual screening and computational simulation identifies photodynamic therapeutics against human Protoporphyrinogen Oxidase IX (hPPO)

Integration of virtual screening and computational simulation identifies photodynamic therapeutics against human Protoporphyrinogen Oxidase IX (hPPO)

Photodynamic therapy (PDT) is a rapidly evolving area of cancer management against solid tumors. PDT is either administrated by injecting photosensitizer (porphyrins) or by accumulation of intracellular protoporphyrin IX via the inhibition of human Protoporphyrinogen Oxidase IX (hPPO). In this study...

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Bibliographic Details
Main Authors: Amir Zeb, Chanin Park, Minky Son, Ayoung Baek, Yeongrae Cho, Donghwan Kim, Shailima Rampogu, Gihwan Lee, Youn-Sig Kwak, Seok Ju Park, Keun Woo Lee
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S187853521830090X

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http://www.sciencedirect.com/science/article/pii/S187853521830090X

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