Pharmacokinetic and Pharmacodynamic Characteristics of Pelubiprofen Tromethamine vs. Pelubiprofen in Healthy Subjects

Pharmacokinetic and Pharmacodynamic Characteristics of Pelubiprofen Tromethamine vs. Pelubiprofen in Healthy Subjects

Compared to pelubiprofen, a cyclooxygenase-2-selective inhibitor, pelubiprofen tromethamine has been reported to exhibit improved solubility and absorption. Pelubiprofen tromethamine combines the anti-inflammatory effect of pelubiprofen with the gastric protective function of tromethamine salt, maki...

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Bibliographic Details
Main Authors:	Yu-Jeong Son, Min-Kyu Park, Hyeon-Jeong Park, Ha-Yeon Kim, Ye-Lim Jang, Young-Sim Choi, Jun-Gi Hwang, Ji-Hyung Seo, Yu-Kyong Kim
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Pharmaceutics
Subjects:	phase I comparative pharmacokinetics/pharmacodynamics tromethamine salt COX-2 inhibitory effect
Online Access:	https://www.mdpi.com/1999-4923/15/4/1280

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