High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds

High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds

Abstract Morphological profiling is an omics-based approach for predicting intracellular targets of chemical compounds in which the dose-dependent morphological changes induced by the compound are systematically compared to the morphological changes in gene-deleted cells. In this study, we developed...

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Bibliographic Details
Main Authors: Shinsuke Ohnuki, Itsuki Ogawa, Kaori Itto-Nakama, Fachuang Lu, Ashish Ranjan, Mehdi Kabbage, Abraham Abera Gebre, Masao Yamashita, Sheena C. Li, Yoko Yashiroda, Satoshi Yoshida, Takeo Usui, Jeff S. Piotrowski, Brenda J. Andrews, Charles Boone, Grant W. Brown, John Ralph, Yoshikazu Ohya
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-022-00212-1

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https://doi.org/10.1038/s41540-022-00212-1

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