5-Fluorouracil and irinotecan (SN-38) have limited impact on colon microbial functionality and composition in vitro

Gastrointestinal mucositis is a debilitating side effect of chemotherapy treatment, with currently no treatment available. As changes in microbial composition have been reported upon chemotherapy treatment in vivo, it is thought that gut microbiota dysbiosis contribute to the mucositis etiology. Yet...

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Bibliographic Details
Main Authors: Eline Vanlancker, Barbara Vanhoecke, Andrea Stringer, Tom Van de Wiele
Format: Article
Language:English
Published: PeerJ Inc. 2017-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/4017.pdf