Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice

Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice

Abstract Glutathione synthetase (GSS) catalyzes the final step in the synthesis of glutathione (GSH), a well-established antioxidant. Research on the specific roles of the Gss gene during spermatogenesis remains limited due to the intricate structure of testis. In this study, we identified pachytene...

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Bibliographic Details
Main Authors: Haixia Zhu, Yin Cheng, Xianmei Wang, Xing Yang, Min Liu, Jun Liu, Shuqiao Liu, Hongxiang Wang, Aizhen Zhang, Runze Li, Chao Ye, Jian Zhang, Jiangang Gao, Xiaolong Fu, Bin Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06359-x

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https://doi.org/10.1038/s41419-023-06359-x

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